STRAIGHT OUTTA LOCASH!!!!!!

My mans posted this joint so I had to, funny as shit

DAY N NIGHT

HUH?

Soooo maybe I'm naive but I thought the 50/Ross was over but I guess not... Ross has put out 2 new diss tracks.... smh

ARE U A COOL KID?

I have to admit that I've been ignorin The Cool Kids since I heard Black mags..... But these bammas be rockin... now I'm on a mission to hear what ever they've been puttin.... guess I'm tryna be a COOL KID :-\

THIS MAN IS RIDICIOULS

Making of "Addiction" from Ryan Leslie on Vimeo.

LADIES KEEP IT CLEAN

There is nothing worse than a women with more hair than a man. With that being said KEEP your underarm, legs, and anywhere other than the top of your head(Cranium) shaved bald. Now I'm not sayin that you have to go prepubescent down stairs, I mean I would never turn a youngin down because she tryna keep her pussy (I'm vulgar deal with it)a lil natural , but trim it up ladies. ST@MP that

BABIES SMH

SANTANA IS THAT MAN

I was going through some old songs and came across some of his features. This man is too vicious on the guitar I just wish there was a video for his Michael Jackson/Santana joint but they don't sooo enjoy

Whatever Happens - Michael Jackson

HAPPY VALENTINES DAY LADIES

HIV VACCINE?

Doctors have succeeded in ridding a man of the HIV virus by giving him a bone marrow transplant in what they claim is the closest treatment yet to a cure for the disease.

The remarkable case gives new impetus to the development of gene therapy for HIV which could ultimately replace the need for expensive and toxic antiretroviral drugs. Instead of taking drugs for life, HIV sufferers might instead have a one-off treatment that would leave them virus-free.

The 42-year-old American had been infected with HIV for a decade. He was treated with antiretroviral drugs in Berlin, where he lives, for four years to hold the disease in check, but then developed leukaemia. Since being given a bone marrow transplant two years ago, he has not taken antiretroviral drugs to control HIV and has had no resurgence of either disease. He is believed to be the longest HIV-free survivor who was previously treated with antiretroviral drugs. Full details of the case are published for the first time today in The New England Journal of Medicine. An editorial in the journal says it "places further emphasis on gene therapies" for HIV, adding: "The case paves the way for innovative approaches that provide long-lasting viral control with limited toxicities for persons with HIV infection."

The man's treatment began with a search by doctors at Berlin's Charité Hospital for a bone marrow donor with a genetic resistance to HIV. One of the strangest features of the disease is the way some people who have been exposed to the virus on many occasions remain uninfected. Twenty years ago, it was noticed that certain prostitutes in Nairobi remained uninfected despite exposure to the virus through thousands of sexual contacts.

It has since emerged that some people carry a mutation of a gene (CCR5) that confers protection against HIV. In Western populations an estimated one to three per cent have the mutation.

Dr Gero Hutter, a haematologist at the Berlin Charité Hospital, and colleagues tested 61 potential donors before they found one with the CCR5 genetic mutation, who agreed to the operation.

The American recipient of the transplant, who runs a holiday rentals business in the German capital, has undergone regular checks in the two years since the treatment. The doctors have tested his bone marrow, blood and tissues and found no sign of HIV. "For as long as the viral load remains undetectable, this patient will not require antiretroviral therapy," they say in the journal.

Speaking to The Independent yesterday, Dr Hutter said there had been several previous reports of patients being virus-free following treatment but none to compare with the latest case. "The difference is that in our patient we had a plan. It was not an accident," he added. "It is the longest time someone who has had antiretroviral therapy and stopped has lasted without the virus rebounding. Normally it rebounds within weeks. It is the closest we have come to a cure."

Dr Hutter said a bone marrow transplant would be too risky as a routine treatment for HIV and too difficult to find donors with the right genetic make-up. But a modification of the approach using gene therapy to render a patient HIV-resistant could work, he said.

Even a costly treatment could be worthwhile. The price of treatment with antiretrovirals in Europe is €70,000 to €80,000 (£63,000 to £72,000) a year compared with a one-off cost of €20,000 to €30,000 for a bone marrow transplant.

Dr Hutter said: "When I started in medicine, HIV was completely untreatable. Now the situation has changed completely. Perhaps our case is a glimpse of hope for the future."

Professor Jay Levy, an Aids specialist at the University of California, and author of the US journal's editorial, said claims that the patient had been cured of HIV would be premature because of the virus's capacity to hide in other parts of the body including the brain, gut, liver and lymphatic system, from which it could always re-emerge.

"Nevertheless, the results... provide further encouragement for those examining approaches to treatment that reduce CCR5 expression in persons with HIV infection," he writes.In 2007, an estimated two million people died from Aids and 2.7 million were newly infected with HIV.

25 years of research: The HIV virus

When the discovery of HIV was announced in 1984, US politicians predicted that a cure for Aids would be found within five years, but it is still a distant prospect.

Over the past 10 years, a cocktail of aggressive antiretroviral drugs has been developed to help keep the effects of the disease at bay. Eliminating it has proved far more difficult because of the virus's unique nature.

HIV integrates itself into an infected person's DNA and attacks the cells the immune system sends to attack it. Once infected, these T-cells take the virus deeper into the body. Gene therapy is a new approach that harnesses the natural resistance to
HIV shared by 3 per cent of people.

Experts hope that by tweaking a sufferer's DNA, they can achieve "long-lasting viral control".

50 CENT'S EITHER?

50 cent's newest shot at Rick Ross is too vicious. This joint makes you forget there was ever a "piggy bank" record. I'm not sure what Rick is thinking but with 50 droppin diss records that would tip Rick's fat ass off the scale who knows where his career will land. Check this joint out it's definitely gonna be crankin on my ipod.

Tia Told Me [Rick Ross Diss] - 50 Cent

I LOVE COLLEGE

I rock wit Asher Roth, I mean even though he sounds like Em a lil he still has his own style, regardless this song cranks

2009 GRAMMY AWARD PERFORMANCES......THE ONES I WANT TO SEE

I forgot the grammys were on, ended up seein some of it at a bar but couldn't hear anything... so here r the preformances that I wanted to see

MR.CHI-CITY'S; CONTINUED BAD LUCK IN 2009

This man is a lunchbox

SYCED AND BLOWN

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FLOATIN ON AIR

Soooo this chair is hot. It's made by this british company called Hoverltd. The chair is called "the lounger" and uses magnets to keep the chair afloat.... The only problem is that this joint cost $8350.00 so I'll stick to admirin it

50 HAS LOST IT

Apparently when a rapper gets money and gets old they start goin crazy, ie: Kanye (fro mullet), T.I. ("and I got the same things like TI), and 50

SHE LOVES EVERYBODY

Heard this joint and I can't stop listenin to it this joint is toooo vicious

THIS IS ONE COOL ASS MAN

LITTLE KID HIGH AS SHIT

RYAN LESLIE - GIBBERISH

When I first heard this joint I was like Nigga GET THE FUCK but after seein the making of it I have a new found appreciation and I guess respect for the man..... well maybe not respect but I like this song a little bit not alotta bit

LIL WAYNE KATIE COURIC INTERVIEW :-\